Endocrine Abstracts

Introduction: Autoimmune adrenal injury is the most common cause of primary adrenal failure (PAF) (70–90%). Antiphospholipid syndrome (APS) that characterized by thrombosis and abortus may be a reason of PAF. In this presentation we reported a case of primary adrenal failure due to primary antiphospholipid syndrome.Case: A 34-year-old boy was brought to emergency service due to loss of consciousness. In physical examination patients was confused, bl...

Introduction: Oncocytic (Hurthle cell) carcinoma is consisted of <5% of thyroid cancer but most metastasizing cancer type among differentiated thyroid cancer. We presented an oncocytic carcinoma with sternum metastasis.Case: A 68-year-old women admitted to endocrinology policlinic with complaint of a mass in her neck. She was diagnosed hyperthyroidism and she was using thionamid for 6 months. Her medical history revealed hypertension for 3 years and ...

Primary mediastinal ectopic goiters are very rare and comprise about 1% of all mediastinal tumors. Blood supply of primary mediastinal goiter comes from local intrathoracic vessels. Compressing symptoms, diagnostic uncertainty, and the risk of malignancy support surgical excision.Case report: The patient is a 40-year-old woman with a 6-month history of progressive dyspnea, chest and back pain. Chest X-ray showed the left superior mediastinal mass was com...

Diffuse sclerosing variant of papillary thyroid carcinoma is a rare variant. It is usually seen in children and young adults.The thyroid gland is diffusely involved. It is characterized by scattered microscopic tumor islands, diffuse fibrosis, calcification, abundant lymphocytic infiltration and psammom body when compared with conventional papillary thyroid carcinoma. Usually the lesion does not cause mass but rather a dominant nodule in one lobe is present in 50% of cases. Ly...

Vitamin D has immunomodulatory features and its deficiency is associated with the development of autoimmune diseases. The relation between vitamin D deficiency and autoimmune thyroiditis has not been investigated much. In the present study, our aim was to study the relation between vitamin D therapy and autoimmune thyroiditis.Fifty-four patients having newly diagnosed Hashimoto thyroiditis (HT) and vitamin D deficiency but requiring no thyroid hormone re...

Introduction: Dopamine agonists such as cabergoline and bromocriptine are used in the treatment of hyperprolactinemia to provide normoprolactinemia, to improve gonodal functions and to decrease the size of tumour if there is. Besides common side effects, fibrosis is another rare side effect of dopamine agonists. Long-term use of these drugs has been reported to cause fibrotic changes in heart valves. In addition, there are a few case reports about dopamine agonist-related pleu...

Introduction: Presence of GH receptor in human skin and its appendages suggests a direct effect of GH on skin characteristics. Wet and oily skin due to hyperhidrosis and increased sebum production were described in acromegaly patients.Objective: The aim of the study was to examine the hydration via capacitance, sebum content, transepidermal water loss, pH and temperature of the skin in patients with acromegaly. The data were compared with that of control...

Aim: To examine the endothelial functions of patients with Sheehan syndrome (SS) and to eveluate the effects of hormone replacement treatment except growth hormone on endothelial functions.Subjects and methods: Twenty-four patients with Sheehan syndrome (PSS) aged 40.83±6.43 yr and 25 healthy control women aged 41.13±6.51 yr (C) were included. Endothelial functions were evaluated with high resolution ultrasonography (flow mediated dilatation:FM...

Introduction: Adrenal schwannoma is an extremely uncommon cause of incidentaloma. It originates from neural sheath Schwann cells of the adrenal gland. Herein, we report a case of left adrenal schwannoma that could not be diagnosed preoperatively.Case report: A 53 years old female morbid obese (BMI: 66.68 kg/m2) patient was referred to endocrinology policlinic because of 5 cm left adrenal mass detected on abdominal screening while preparing pat...

Objectives: The novel coronavirus disease-2019 (COVID-19) is the fastest-spreading disease worldwide, with over 380 million cases and 5 million deaths. The presence of diabetes mellitus (DM) in patients with COVID-19 was associated with mortality, acute respiratory distress syndrome, disease progression. COVID-19 was progressed with some hematological disorders, especially lymphopenia. Studies implicated that neutrophil-to-lymphocyte ratio (NLR) level can be a reliable marker ...